Breast Cancer Disparities in African American Women
December 9, 2018 | Blog Post
“African American Women are disproportionately affected by Breast Cancer”
Breast cancer is one of the commonly diagnosed cancers, with over 12% of women experiencing it in their lifetimes [i]. Over 300,000 women were projected to be diagnosed with breast cancer and over 40,000 women were expected to die from it in 2018 . Although overall breast cancer death rates have been decreasing in the last 30 years, the CDC found that 5-year survival rates for African American/black women is 10% less than other races [i, ii]. Incidences of breast cancer are higher in white women, but African American/black women have a higher mortality rate--and this gap is only increasing [iii].
NIH studies have partially attributed this disparity to the higher rates of behavioral risk factors in African American/black women [v]. Additionally, data indicates that minorities are more likely to be impacted by lack of proper social support structures, and their health is consequently affected: living in underserved areas prevents women from receiving quality and appropriate screenings and treatment [v]. Other contributing factors may include cultural differences and a lack of trust in the healthcare system [v].
African American/black women are more likely to have triple-negative breast cancer, which is more aggressive and has a worse prognosis than hormone-positive cancers, which are more common in white women [vi]. Studies have shown that social and environmental stressors that African American/black women experience such as segregation, perceived discrimination, and social isolation are associated with molecular changes causing HR- breast cancer subtypes [viii]. The NIH suggests that this biological difference may be reflected in fewer clinical trials targeted towards minority women [v].
Furthermore, African American/black women are now more likely to get regular mammography screenings than white women, yet their prognosis is still worse [iv]. A study in South Carolina found that African American/black women were more likely to adhere strictly to mammogram screening guidelines, but were still more likely to be diagnosed with late-stage breast cancer, suggesting a need for more frequent or earlier stages of screening [vi].
In St. Louis, researchers found that African American/black women diagnosed with breast cancer were more likely to lose their job and less likely to undergo immediate treatment compared to white women and that over 50% of them never receive treatment at all [vii].
As more research emerges about the causes and effects of health inequities that African American/black women with breast cancer experience, there likewise needs to be an increase in efforts to combat this imbalance. Researchers have called for more research on targeted drug therapy for triple-negative breast cancer, more interventions to improve adherence to breast cancer treatments, and more African American/black female representation in clinical trials, biobanks, and genomic testing [viii]. Additionally, there have been a number of recent efforts to improve the prognosis of African American/black women by improving access to screening and providing patient navigation programs [viii]. For more information on this important health equity topic, join us for our 9th annual Diversity, Inclusion, & Health Equity Symposium in June 2019 in Chicago.
Healthcare Analyst at CHI
Joseph Gaspero is the CEO and Co-Founder of CHI. He is a healthcare executive, strategist, and researcher. He co-founded CHI in 2009 to be an independent, objective, and interdisciplinary research and education institute for healthcare. Joseph leads CHI’s research and education initiatives focusing on including patient-driven healthcare, patient engagement, clinical trials, drug pricing, and other pressing healthcare issues. He sets and executes CHI’s strategy, devises marketing tactics, leads fundraising efforts, and manages CHI’s Management team. Joseph is passionate and committed to making healthcare and our world a better place. His leadership stems from a wide array of experiences, including founding and operating several non-profit and for-profit organizations, serving in the U.S. Air Force in support of 2 foreign wars, and deriving expertise from time spent in industries such as healthcare, financial services, and marketing. Joseph’s skills include strategy, management, entrepreneurship, healthcare, clinical trials, diversity & inclusion, life sciences, research, marketing, and finance. He has lived in six countries, traveled to over 30 more, and speaks 3 languages, all which help him view business strategy through the prism of a global, interconnected 21st century. Joseph has a B.S. in Finance from the University of Illinois at Chicago. When he’s not immersed in his work at CHI, he spends his time snowboarding backcountry, skydiving, mountain biking, volunteering, engaging in MMA, and rock climbing.