Reducing Clinical Trial Cost & Dropouts

May 8, 2018  |  Best Practice

1. Recognize Why Patients Drop Out

Recognize patients drop out of clinical trials because of inconvenient locations, schedule conflicts, forgetting visits, fear and anxiety, financial constraints, family matters, side effects, and failure of the condition to improve.

2. Encourage Providers to Engage Patients 

Encourage better communication between providers and patients and accommodate patient preferences to help engage patients and encourage compliance throughout the length of the clinical study.

3. Provide Information & Education 

Lack of knowledge about the clinical trial process creates barriers. Clinicians should educate the participants regarding the trial process, expectations, and address any concerns in an approachable manner.

4. Appreciate Patients’ Values, Culture, Preference & Needs

Patients from various backgrounds, ethnicities, and socioeconomic statuses participate in clinical trials. At all stages of the clinical trial process, it is important that patients feel that their values and preferences are being respected.

5. Engage Family & Friends

Engaging family and friends sit at the core of patient-centeredness. Properly educated family and friends can answer patient questions, keep them motivated, and keep them compliant with the trial protocol.


To learn more health equity best practices, attend an upcoming CHI educational event.


Joseph Gaspero is the CEO and Co-Founder of CHI. He is a healthcare executive, strategist, and researcher. He co-founded CHI in 2009 to be an independent, objective, and interdisciplinary research and education institute for healthcare. Joseph leads CHI’s research and education initiatives focusing on including patient-driven healthcare, patient engagement, clinical trials, drug pricing, and other pressing healthcare issues. He sets and executes CHI’s strategy, devises marketing tactics, leads fundraising efforts, and manages CHI’s Management team. Joseph is passionate and committed to making healthcare and our world a better place. His leadership stems from a wide array of experiences, including founding and operating several non-profit and for-profit organizations, serving in the U.S. Air Force in support of 2 foreign wars, and deriving expertise from time spent in industries such as healthcare, financial services, and marketing. Joseph’s skills include strategy, management, entrepreneurship, healthcare, clinical trials, diversity & inclusion, life sciences, research, marketing, and finance. He has lived in six countries, traveled to over 30 more, and speaks 3 languages, all which help him view business strategy through the prism of a global, interconnected 21st century. Joseph has a B.S. in Finance from the University of Illinois at Chicago. When he’s not immersed in his work at CHI, he spends his time snowboarding backcountry, skydiving, mountain biking, volunteering, engaging in MMA, and rock climbing.